内镜下治疗非静脉曲张性上消化道出血98例疗效分析

Analysis of clinical efficacy of treating nonvariceal upper gastrointestinal bleeding under endoscopy in 98 patients

目的总结内镜下治疗非静脉曲张性上消化道出血(NVUGIB)的疗效。方法 60岁以上NVUGIB患者98例,随机均分为两组:B组采用内镜下局部注射止血治疗;A组在此基础上加用金属夹止血。比较两组的止血效果和术后感染发生率。结果术后72h之内,A组止血有效率100%(49/49),高于B组的81.6%(40/49)(P<0.05)。A组止血成功率95.9%(47/49),高于B组的77.6%(38/49)(P<0.05)。A组术后感染发生率低于B组(4.1%vs.16.3%)(P<0.05)。结论采用内镜下局部注射联合金属夹止血法治疗NVUGIB的止血效果优于单用局部注射,安全性高。

Objective To summerise the clinical efficacy of treating nonvariceal upper gastrointestinal bleeding（NVUGIB） under endoscopy in 98 patients. Methods A total of 98 cases aged over 60 years old was equally divided into two groups. The patients in group B were treated by local injection for hemostasis and those in group A were given additional metal clip. The clinical efficacy of hemostasis and complications were compared between two groups. Results The effectiveness rate of hemostasis in 72 hours after operation was 100 %in group A（49/49）, which was higher than 81.6% （40/49）in group B（P〈0. 05）. The success rate of hemostasis in group A was 95.9%（47/49） ,which was higher than 77.6% （38/49） in group B（P〈0. 05）. The incidence rate of postoperative infection was lower in group A than that in group B（4. 1%vs. 16.3%）（P〈0. 05）. Conclusion It is more effective and safe to treat NVUGIB by endoscope-assisted local injection combined with metal clip than local injection alone.