七氟醚对不同年龄段患者血压的影响

Effects of sevoflurane on blood pressure in patients with different ages

目的：探讨七氟醚麻醉维持中不同年龄段患者血压的改变及最适浓度。方法按常规手术安排顺序收入择期行腹腔镜胆囊切除术（ LC）患者60例,常规诱导,全程吸入七氟醚维持麻醉,按年龄分为青年组34例,中年组20例,老年组6例。记录诱导前及麻醉维持后10 min（T1）、20 min（T2）、30 min（T3）、60 min（T4）的SBP、DBP、MAP、呼气末七氟醚浓度（CETsev）及各浓度下患者例数、年龄。结果麻醉维持后血压波动在正常范围,维持后MAP在诱导前MAP ±20%范围内波动。各时间点不同CETsev下患者年龄比较差异无统计学意义（P〉0.05）。各时间点不同CETsev下患者年龄段构成比差异无统计学意义（P〉0.05）。随麻醉时间延长,0%~1%CETsev下患者例数由35例下降至11例,1%~2%时由10例上升至20例,2%~3%时维持在14例左右。结论 CETsev对不同年龄段患者血压的影响近似,2%~3%CETsev在各年龄段是既能满足手术需要,又能维持循环稳定的最适浓度。

Objective To investigate the effect of sevoflurane on blood pressure in patients with different ages and the optimal concen-tration of sevoflurane. Methods 60 patients underwent selective LC operation with conventional induction and sevoflurane maintenance were divided into three groups：the youth group （34 patients）, the middle age group （20 patients） and the older age group （6 patients）. The SBP, DBP, MAP, CETsev, number of patients, age of patients before induction and 10 min（T1）, 20 min（T2）, 30 min （T3）, 60 min （T4） after induction were recorded. Results Fluctuate of blood pressure were in the normal range after anesthesia maintenance, and MAP were fluctuated within the range of ± 20% before induction. The age under different CETsev were of no significant difference in each time point （P〉0. 05）. The age composition ratio in different CETsev were of no significant difference in each time point （P〉0. 05）. As the time of anesthesia extended, the number of patients under 0% ~1%CETsev decreased from 35 to 11; the number of patients under 1% ~2%CETsev increased from 10 to 20;and the number of patients under 2% ~3%CETsev maintened in 14 approximately. Conclusion The effect of sevoflurane on blood pressure of different ages is approximate. 2% ~3% CETsev is the most optimal concentration during the main-tenance of anesthesia.