2007-2014年广州市海珠区麻疹风疹疑似病例血清学检测结果分析

Analysis of serological detection results of suspected measles and rubella cases in Haizhu district of Guangzhou from 2007 to 2014

目的分析2007-2014年广州市海珠区麻疹及风疹流行特征,为疾病防控提供科学依据。方法采用酶联免疫吸附法(ELISA)对疑似麻疹、风疹病例血清标本进行Ig M抗体检测,SPSS13.0软件统计分析检测结果。结果共检测样本2 281例,麻疹Ig M抗体阳性总检出率为33.14%,风疹Ig M抗体阳性总检出率为7.85%,不同年份之间麻疹、风疹阳性率差异有统计学意义(χ2=415.805,P=0.000;χ2=143.681,P=0.000)。不同年份之间麻疹、风疹阳性病例性别分布差异无统计学意义。麻疹发病高峰主要在3-7月,0~5岁婴幼儿及15~29岁中青年高发;风疹发病高峰集中在3-6月份,15~25岁青少年为主要发病人群。结论 8年间辖区内麻疹阳性率有明显波动,近3年呈上升趋势,应引起足够重视。要达到消除麻疹控制风疹的目标,必须持续做好计划免疫,严密监测,控制暴发。

Objective To analyze the epidemic feature of measles in Haizhu district of Guangzhou during 2007-2014,and provide scientific basis for disease control and prevention.Methods All the suspected cases were tested for measles and rubella specific Ig M antibody by ELISA during 2007-2014.The data were analyzed by SPSS13.0.Results From 2007-2014,toatally 2 281 samples were detected,and the positive rate of measles and rubella of Ig M antibody were 33.14% and 7.85%,respectively.There was no statistical difference between male and female both in measles and rubella cases.The morbidity peak of measles was from March to July;incidence was higher between 0~5 and 15~29 years old.The positive cases of rubella was mainly distributed in March^June and the incidence was higher in 15~25 years old.Conclusion The decreasing trend of positive rate of measles in 2010 and 2011 indicated the control measures were effective,but in the last three years the incidence of measles were increasing,indicated that we should pay more attention and promptly prevent the outbreak and epidemic of the disease.