摘要
Hepatitis B virus （HBV） has a unique rela- tionship with humans. It is not only very suc- cessful in spreading amongst our species （a third of the human population has been in contact with the virus and approximately 200-300 million people are actively infected）, but it has adapted to and co-evolved with us. This long-term relationship is demonstrated by the recent detection of hepadnavirus gen- omes in Mesozoic birds2 and by the estima- tion that HBV was already present in early humans at least 40, 000 years ago.3
Hepatitis B virus （HBV） has a unique rela- tionship with humans. It is not only very suc- cessful in spreading amongst our species （a third of the human population has been in contact with the virus and approximately 200-300 million people are actively infected）, but it has adapted to and co-evolved with us. This long-term relationship is demonstrated by the recent detection of hepadnavirus gen- omes in Mesozoic birds2 and by the estima- tion that HBV was already present in early humans at least 40, 000 years ago.3
