嗜酸细胞性胃肠炎2例报道

Eosinophilic gastroenteritis: 2 cases report

嗜酸细胞性胃肠炎是一种病因不明的少见疾病。是以胃肠黏膜组织中嗜酸细胞浸润,具有不同的浸润深度和症状为特点的消化道疾病。嗜酸细胞性胃肠炎典型临床表现有腹痛、腹水、恶心、呕吐、腹泻、体质量减轻等症状。约80%患者的症状可持续数年。由于本病少见,因此其诊断常较困难。本文报道2例以腹胀及腹痛为主要表现的患者,结合其病史综合判断,最后诊断为嗜酸性胃肠炎。

Eosinophilic gastroenteritis is a rare disease of unknown etiology. It is characterized by eosinophilic infiltration of the bowel wall to a variable depth and symptoms associated with gastrointestinal tract. Eosinophilic gastroenteritis typically presents with a combination of chronic nonspecific gastrointestinal symptoms which include abdominal pain, ascites, nausea, vomiting, diarrhea, weight loss, and abdom- inal distension. Approximately 80% of the patients have symptoms for several years. A high degree of clinical suspicion is often required to establish the diagnosis, this disease is extremely rare. Two cases who presented with ventosity and abdominal pain were reported. Taking the full clinical history and a meticulous investigation finally led to the diagnosis.