儿童喘息与细菌关系的研究进展

Research progress in the relationship between childhood wheezing and bacteria

喘息是儿童时期最常见的呼吸系统疾病临床表现之一,主要与病毒感染有关。近年来有文献报道细菌在呼吸道的定植或感染也可能与儿童喘息,尤其是婴幼儿喘息相关。气道中发现这些菌群是一种正常的临床现象,还是其中部分细菌引起了儿童反复喘息,以及其在喘息性疾病发生发展中的作用与机制,目前尚不完全清楚。该文主要综述儿童喘息与细菌关系及细菌引起儿童喘息的可能机制的最新研究进展。

Wheezing is one of the most common clinical manifestations of childhood respiratory diseases, mainly associated with virus infection. Recent years, bacteria colonization and its infection are reported to involve in childhood wheezing, especially in infantile wheezing. However, the bacteria lfora in the airway is only a phenomenon or a reason to induce some childhood wheezing, and its roles, as well as the mechanism in the development of wheezing remain unknown. This article summarizes the research progress in the relationship between childhood wheezing and bacteria and in the possible mechanisms of childhood wheezing caused by bacteria.