二维彩色血流汇聚法定量评估二尖瓣偏心性反流程度的价值

Assessment of eccentric mitral regurgitation by two-dimension proximal isovelocity surface area

目的 探讨二维彩色血流汇聚法（2D-PISA）定量评价二尖瓣偏心性反流程度的价值.方法 选择单纯性二尖瓣偏心性反流患者31例,用2D-PISA法定量评价二尖瓣反流相关参数,以心脏磁共振（CMR）结果为标准,分析两者的相关性,建立线性回归方程.结果 2D-PISA法有效反流口面积（EROA2D-PSA）为（0.19±0.07）cm2,反流容积（RV2D-PSA）为（28.74±9.51）ml,反流分数（RF2D-PISA）为（24.28±7.95）％;CMR法反流容积（RVCMR）中位数为24.0 ml,四分位数间距为15.75 ml,反流分数（RFCMR）为（35.38±14.89）％.各参数2D-PISA法与CMR法间存在良好的相关性,相关系数均＞0.60,P均＜0.01;EROA2D-mA＆amp;RFCMR间直线回归方程为Y=7.24＋149.011 X,RF2D-PISA＆amp;RFCMR间直线回归方程为Y=7.216＋1.16 X.结论 2D-PISA法可较准确地定量评价二尖瓣偏心性反流程度,有良好的应用前景.

Objective To evaluate the value of two-dimension proximal isovelocity surface area （2D- PISA） in quantitative diagnosis of eccentric mitral regurgitation （EMR）. Methods The parameter of EMR was collected with 2D-PISA in 31 patients. The results were compared with corresponding measurements obtained by cardiac magnetic resonance imaging （CMR）, and analyzed their correlation and regression based on the CMR method as a ＂reference standard＂. Results The mean EROA2D_PSA was （0.19± 0.07）cm2, mean RV2D_PSA was （28.74± 9.51）ml and mean RF2D-PSA was （24.28± 7.95）%. The median RVCNR was 24.00 ml, the interquartile range was 15.75 ml, the mean RFCMR was （35.38＋14.89）%. There was good correlation between the EMR parameter ob- tained by 2D-PISA method and CMR method （r〉0.60, P〈0.01 ）. The regression equations between EROA2D_PSA ＆ RFCMR was Y=7.24＋149.011 X, and between RF2D_PSA ＆ RFCMR was Y=7.216＋1.16 X. Conclusion 2D-PISA is a accurate method to quantitative diagnosis of EMR, it would be widely used in clinic.