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抗苗勒管激素在临床中的应用与研究进展 被引量:8

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摘要 抗苗勒管激素(AMH)是目前倍受关注的女性生殖生理调节因子之一。抗苗勒管激素(AMH)由卵巢窦前卵泡及小窦状卵泡颗粒细胞分泌,不受促性腺激素的反馈调节,可早期、准确评估卵巢储备功能,相对提高辅助生殖技术(ART)的成功率;AMH可抑制卵泡的募集、选择,对卵泡障碍性疾病如多囊卵巢综合征(PCOS)和卵巢早衰(POF)的发病机制诊断有重要价值。研究表明,AMH较其它卵巢功能评价指标如FSH、LH、E2更能准确反映生育年龄女性机体内分泌状态,有望成为评估卵巢功能的新指标。国外已将AMH用于评估卵巢储备功能。鉴于AMH在临床应用的广阔前景,了解国内生育期女性血清AMH水平非常有必要。
出处 《青海医药杂志》 2015年第4期77-79,F0004,共4页 Qinghai Medical Journal
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