电针足三里穴对FGID模型大鼠多脏器微循环的影响

Effect of Electroacupuncture Zusanli on Microcirculation of Various Organs of Experimental Rats Model of Gastrointestinal Disorder

目的 :观察电针刺激足三里穴对胃肠功能紊乱(FGID)模型大鼠多脏器微循环的影响,研究电针刺激对FGID模型大鼠胃肠功能的调理作用,并通过比较、分析电针对大鼠胃、肠、肝、脑各脏器微循环所产生影响的差异,初步探讨穴位内脏效应的规律。方法:使用电针治疗仪对GID模型大鼠足三里穴进行刺激,采用激光多普勒血流仪同步监测胃、十二指肠、肝、脑等脏器表面微循环,对所得数据进行统计学分析。结果:电针GID模型大鼠足三里穴可以明显改善胃、肠表面微循环状况,增加其微循环血流量,并在停针后维持在一个较高水平,对肝、脑微循环影响无显著性差异,P>0.05。结论:对足三里穴进行电针刺激能够有效调节FGID模型大鼠胃、肠道微循环,对胃肠功能紊乱起到积极的治疗作用,并且对胃、肠两脏器微循环血流量的影响显示出相对特异性。

Objective：To observe the eitect of stimulating at Zusanli acupoint by electroacupunctureon microcirculation of various organs of model rats of gastrointestinal disorders （GID）, study the regulating effects of electroacupuncture on gastrointestinal function of model rats of GID and compare and analyze the differences of the effects of electroacupuncture on microcirculation of rats＇ stomach,intestine,liver and brain,so as to explore the rules of acupoint effects on internal organs. Methods：The Zusanli acupoint of model rats of GID was stimulated by electroacupuncture instrument. The laser doppler flowmetry was used to monitor the superficial microcirculation of stomach,duodenum,liver,brain and other organs synchronously. The data get from the experiment was statistically analyzed. Results：Electroacupuncture on Zusanli acupoint of model rats of GID could significantly improve the condition of superficial microcirculation of stomach and intestine. It could increase the microcirculation blood flow and maintain it at a high level when the acupuncture was stopped. The effect on microcirculation of liver and brain was .not statistically significant. Conclusion：Electroacupuncture on Zusanli can effectively regulate the gastric and intestinal microcirculation of model of rats of GID. It had a positive curative effect on gastrointestinal disorders. The effect on the microcirculation blood flow of stomach and intestine showed relative specificity.