摘要
Two new homosecoiridoids, named loniaceticiridoside （1） and lonimalondialiridoside （2）, were isolated from an aqueous extract of the flower buds of Lonicera japonica. Their structures including the absolute configuration were determined by extensive spectroscopic studies, especially by 2D NMR and CD data analysis. A proposed biosynthetic pathway and preliminary investigations of the biological activity of compounds 1 and 2 are also discussed.
Two new homosecoiridoids, named loniaceticiridoside （1） and lonimalondialiridoside （2）, were isolated from an aqueous extract of the flower buds of Lonicera japonica. Their structures including the absolute configuration were determined by extensive spectroscopic studies, especially by 2D NMR and CD data analysis. A proposed biosynthetic pathway and preliminary investigations of the biological activity of compounds 1 and 2 are also discussed.
基金
Financial support from the National Natural Science Foundation of China(NNSFC
Nos.20772156 and 30825044)
the Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT,No.IRT1007)
the National Science and Technology Project of China(Nos.2012ZX09301002-002 and 2011ZX0 9307002-01) is acknowledged
