化痰降浊汤对高脂血症患者血管内皮的保护作用

Huatan Jiangzhuo decoction on vascular endothelium protection of patients with hyperlipidemia

目的观察自拟化痰降浊汤对高脂血症患者血管内皮保护作用,为其临床推广应用提供客观真实的科学依据。方法选取40例符合高脂血症诊断标准,但无明显临床症状的患者按随机对照表分为2组,化痰降浊汤组和血脂康组。观察2组患者治疗前后血清超氧化物歧化酶(SOD)活性、丙二醛(MDA)含量的变化。结果用药30 d后,各组患者血清SOD活性显著提高,MDA含量显著降低(P<0.01)。结论化痰降浊汤通过健脾化痰,使机体内气血调和,痰随气化,脂浊自灭,达到降脂,保护血管内皮的目的。

Objective To observe Huatan Jiangzhuo decoction on vascular endothelium protective function in patients with hyperlipidemia and for its clinical application to provide objective and truthful scientific basis. Methods Selected 40 cases of hyperlipidemia diagnosis standard,but have no obvious clinical symptoms of patients according to the random table divided into two groups： Huatan Jiangzhuo decoction group and Xuezhikang group. Observe two groups of patients before and after treatment serum superoxide dismutase（ SOD） activity and malondialdehyde（ MDA） content changes. Results After 30 d,two groups of patients with significantly higher serum SOD activity and MDA content obviously decreased（ P 〈0. 01）. Conclusion Through invigorating spleen to reduce phlegm,Huatan Jiangzhuo decoction to make the body＇s balance of qi and blood,reduce phlegm from qi,lipid turbidity self-quenching,achieving lipid-lowering and the purpose of protecting vascular endothelium.