摘要
目的研究肺结核患者感染产β-内酰胺酶(ESBL)粘质沙雷菌临床特点及其耐药状况。方法通过回顾性调查方法,对某医院住院肺结核患者痰液标本检测资料进行了统计分析。结果某医院自2009-2013年期间从住院结核病患者送检痰标本中共检出粘质沙雷菌132株,其中含产ESBLs菌37株,占28.0%。结核病患者感染的粘质沙雷菌对常用抗菌药物有不同程度耐药,对头孢类、氨苄西林和氨曲南耐药率均>60%。结论肺结核患者感染的粘质沙雷菌耐药严重,应根据药敏试验结果合理选用抗菌药物。
Objective To study the clinical characteristic and drug resistance of patients with pulmonary tuberculosis were infected by 13 - lactamase - producing Serratia marcescens. Methods Retrospective investigation was used to statistical a- nalysis of the sputum samples data of hospitalized patients with pulmonary tuberculosis in a hospital. Results 132 strains of Serratia marcescens were detected from the samples of sputum specimens in a hospital in the period 2009 -2013 hospitalized patients with pulmonary tuberculosis ,which included 37 strains of ESBLs producing Serratia marcescens, the detection rate was 28. 0%. Serratia marcescens of patients with pulmonary tuberculosis infected have different degrees of resistance to com- monly used antibiotics, the resistance rates to cephalosporin antibiotics, ampicillin and ammonia were all above 60% Conclusion Drug resistance of Serratia marcescens of patients with pulmonary tuberculosis infected was serious, clinicians should choose the antibiotics according to the results of drug sensitive test.
出处
《中国消毒学杂志》
CAS
北大核心
2015年第5期455-457,共3页
Chinese Journal of Disinfection
关键词
肺结核
粘质沙雷菌
肺部感染
耐药性
pulmonary tuberculosis
Serratia marcescens
lung infection
drug resistance