320例百草枯中毒病例救治回顾分析

Retrospective analysis of the treatment of 320 paraquat poisoning cases

目的:分析百草枯(PQ)中毒患者的年龄、性别因素,及时洗胃、血液净化治疗、抗炎和免疫抑制治疗对患者治疗效果的影响,为正确预防治疗PQ中毒、提高抢救成功率提供参考。方法:选取2006-01-2014-12在第四军医大学唐都医院急诊科就诊的PQ患者320例,对年龄、性别、临床表现、治疗方案及预后等临床资料进行回顾性分析。结果:1PQ中毒发病具有明显的年龄和性别分布,以青中年女性为主;2及时洗胃、导泻和血液净化治疗对PQ中毒的抢救成功率具有积极影响;3抗炎和免疫抑制治疗能够提高死亡患者的生存时间,但对死亡率无明显影响。结论:尽早洗胃、导泻及血液净化治疗对提高PQ中毒抢救成功率具有积极意义,抗炎和免疫抑制治疗能够提高死亡患者的生存时间。

Objective：To investigate age, gender, gastric lavage, blood purtllcanon tnerapy as eaHy a~ pu~ and anti-inflammatory and immunosuppressive therapy on the effects of the treatment of the paraquat poisoning pa- tients. To provide selection reference for correct prevention and control of paraquat poisoning and improving the rescue success rate. Method：320 paraquat poisoning patients between January 2006 and December 2014 of emergen- cy department Tangdu hospital in the fourth military medical university were chosen, clinical data of age, sex, treat- ment and prognosis were retrospectively analyzed. Result： （1）Paraquat poisoning has obvious age and sex distribu- tion, （2）Gastric lavage, catharsis, and blood purification therapy as early as possible have positive effects on the res cue success rate of paraquat poisoning,（3）The anti-inflammatory and immunosuppressive therapy can improve sur- vival time,but had no significant effect on mortality. Conclusion： Gastric lavage, catharsis, and blood purification treatment can play a positive role to improve the success rate of rescue,anti-inflammatory and immunosuppressive therapy can improve the patient＇s survival time.