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Curvature-induced lipid segregation

Curvature-induced lipid segregation
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摘要 We investigate how an externally imposed curvature influences lipid segregation on two-phase-coexistent membranes. We show that the bending-modulus contrast of the two phases and the curvature act together to yield a reduced effective line tension. On largely curved membranes, a state of multiple domains (or rafts) forms due to a mechanism analogous to that causing magnetic-vortex formation in type-II superconductors. We determine the criterion for such a multi-domain state to occur; we then calculate respectively the size of the domains formed on cylindrically and spherically curved membranes. We investigate how an externally imposed curvature influences lipid segregation on two-phase-coexistent membranes. We show that the bending-modulus contrast of the two phases and the curvature act together to yield a reduced effective line tension. On largely curved membranes, a state of multiple domains (or rafts) forms due to a mechanism analogous to that causing magnetic-vortex formation in type-II superconductors. We determine the criterion for such a multi-domain state to occur; we then calculate respectively the size of the domains formed on cylindrically and spherically curved membranes.
出处 《Chinese Physics B》 SCIE EI CAS CSCD 2015年第6期95-99,共5页 中国物理B(英文版)
基金 Project supported by the Hundred-Talent Program of the Chinese Academy of Sciences(FY) the National Science Foundation of USA via Grant DMR-1106014(RLBS,JVS)
关键词 CURVATURE phase separation lipid membrane RAFTS curvature, phase separation, lipid membrane, rafts
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