儿童重症支原体肺炎临床特征及危险因素分析

Clinical features and risk factors of severe cases of children mycoplasma pneumonia

目的：探讨重症支原体肺炎（ SMPP）患儿的临床特征和危险因素，为防治SMPP提供依据。方法回顾性收集52例SMPP病例和104例轻症MPP病例，比较重症组和轻症组的临床特征，分析影响SMPP发病的危险因素。结果重症组与轻症组相比，具有热程长、病程长、外周血WBC高、CRP高、ESR高、MP－IgM阳性率高、下叶病变部位比例高、大片状病变类型多见、大环内脂使用时间长等特点；影响SMPP发病的危险因素包括CRP（OR＝6．228）、ESR（OR＝3畅877）、MP－IgM阳性（OR＝8．224）、下叶病变部位（OR＝6．987）及大片状病变类型（OR＝11．462）。结论初步掌握了SMPP的主要临床特征及其相关危险因素，为临床早发现、早诊断、早治疗SMPP提供依据。

Objective To explore clinical features and risk factors of severe cases of mycoplasma pneumoniae pneumoni-a （ SMPP） , provide basis for preventing and treating SMPP.Methods Retrospectively collected 52 cases of SMPP and 104 ca-ses of MPP, then compared clinical features between mild case group and severe case group, and analyzed the risk factors of inci-dence of SMPP.Results The severe case group contrast with the mild case group, existedlonger fever lasting time, longer course of disease, more WBC, higher CRP and ESR, higher positive rate of MP-IgM, much higher ratios of hypophyll diseased region, more large patches of the type of lesion and longer use time of large ring lactone.The risk factors of SMPP included in CRP （OR=6.228）, ESR （OR=3.877）, MP-IgM positivity （OR=8.244）, hypophyll diseased region （OR=6.987） and large patches of the type of lesion （OR=11.462）.Conclusion We learned the clinical features and the risk factors of severe HFMD.These might provide clinical basis for early detection, early diagnosis and early treatment of severe HFMD.