狼疮性肾炎的治疗策略:依据病理指导临床

Therapeutic strategy for lupus nephritis: to guide clinical practice based on pathology

狼疮性肾炎是系统性红斑狼疮较常见且严重的并发症,其传统治疗方案制定的主要依据是以经典的肾小球病变为基础的狼疮性肾炎的病理分型。某些特殊的肾脏病理改变及其相关发病机制的提出,为进一步开展精准的个体化治疗提供了更多的可能。

Lupus nephritis is a common and severe complication in systemic lupus erythematosus （SLE）. Traditional therapy of lupus nephritis mainly depends on renal pathological classification profoundly based on glomerular lesions. Moreover, the importance of certain special renal histopathological damages and the corresponding pathogenesis would further contribute to individualized therapy of lupus nephritis.