摘要
为了筛选南瓜籽油降脂效果的生物标志物,将36只SPF级KM系雄性小鼠随机分为对照组、高脂组、南瓜籽油干预组。喂养4周后处死,使用气相色谱-质谱检测血清脂肪酸的种类与含量。结果表明,各组小鼠血清脂肪酸种类无差别;而脂肪酸C16∶1、C18∶1、C18∶2、C22∶6的含量变化显著(p<0.05)。因此,小鼠血清脂肪酸C16∶1、C18∶1、C18∶2、C22∶6可做为南瓜籽油降脂的生物标志物。
Biomarkers of serum fatty acids in lipid-lowering model of pumpkin seed oil need to be elucidated. 36 SPF KM male mice were randomly divided into 3 groups,control, high-fat, PSO intervention. After continuously feeding four weeks, the content of serum fatty acids were detected with gas chromatography-mass spectrometry. No species differences existed in all these groups. The contents of C16:1 ,C18:1 ,C18:2,C22:6 were significantly different between these groups(p〈0.05). Thus the oil adjusted the serum fatty acid profile of hyperlipidemic mice-C 16:1, C 18:1, C 18:2, C22:6.
出处
《食品工业科技》
CAS
CSCD
北大核心
2015年第12期341-343,共3页
Science and Technology of Food Industry
基金
国家自然科学基金项目(31371783)
湖北省自然科学基金(2012FFB04802)