摘要
为了筛选南瓜籽油降脂效果的生物标志物,将36只SPF级KM系雄性小鼠随机分为对照组、高脂组、南瓜籽油干预组。喂养4周后处死,使用气相色谱-质谱检测血清脂肪酸的种类与含量。结果表明,各组小鼠血清脂肪酸种类无差别;而脂肪酸C16∶1、C18∶1、C18∶2、C22∶6的含量变化显著(p<0.05)。因此,小鼠血清脂肪酸C16∶1、C18∶1、C18∶2、C22∶6可做为南瓜籽油降脂的生物标志物。
Biomarkers of serum fatty acids in lipid-lowering model of pumpkin seed oil need to be elucidated. 36 SPF KM male mice were randomly divided into 3 groups,control, high-fat, PSO intervention. After continuously feeding four weeks, the content of serum fatty acids were detected with gas chromatography-mass spectrometry. No species differences existed in all these groups. The contents of C16：1 ,C18：1 ,C18：2,C22：6 were significantly different between these groups（p〈0.05）. Thus the oil adjusted the serum fatty acid profile of hyperlipidemic mice-C 16：1, C 18：1, C 18：2, C22：6.
出处
《食品工业科技》
CAS
CSCD
北大核心
2015年第12期341-343,共3页
Science and Technology of Food Industry
基金
国家自然科学基金项目(31371783)
湖北省自然科学基金(2012FFB04802)
