加味三香汤治疗肠道气滞兼脾虚型功能性便秘的临床疗效观察

Clinical Observation on Jiawei Sanxiang Decoction in the Treatment of Intestinal Qi Stagnation and Spleen Deficiency Type of Functional Constipation

目的:观察加味三香汤治疗肠道气滞兼脾虚型功能性便秘的临床疗效。方法:将80例肠道气滞兼脾虚型功能性便秘的患者随机分为治疗组和对照组,每组40例,治疗组给予加味三香汤口服,对照组给予聚乙二醇4000散剂口服,共治疗14 d,观察患者排便间隔时间、每次排便所需时间、大便的性状,以及少腹胀痛、嗳气、胸胁胀闷疼痛、神疲懒言、体倦乏力的中医症状,记录SAS积分。结果:2组治疗功能性便秘的疗效比较,差异无统计学意义(P>0.05﹚。2组治疗后大便性状的比较,差异无统计学意义。治疗后治疗组中医证候积分及SAS积分明显低于对照组,差异有统计学意义(P<0.05﹚。结论:加味三香汤能够有效治疗肠道气滞兼脾虚型功能性便秘,并且能改善患者的中医证候及焦虑状态。

Objective： To observe the effect of Jiawei Sanxiang Decoction in treating intestinal qi stagnation and spleen deficiencytype of functional constipation.Methods： Eighty cases of patients with intestinal qi stagnation and spleen deficiency type of func -tional constipation were randomly divided into treatment group and control group , with 40 cases in each group.The treatment groupwas given Jiawei Sanxiang Decoction , while the control group was given orally taken polyethylene glycol 4000 powder.The durationof treatment had lasted for 14 days.Records was taken in regard to Traditional Chinese Medicine symptoms , specifically, defecationintervals, defecating time, stool characters, distending pain in the lower abdomen, chest and hypochondrium distension stuffypain, belching, lassitude and disinclination to words, and fatigue symptom, and assessed by SAS integral.Results： There are nosignificant difference in curative effect on functional constipation and improvement on stool character between the two groups .（P 〉0.05） However, after the treatment, TCM syndrome integral and SAS integral in the treatment group were significantly lower thanthose of the control group, and the difference was of statistical significance （P 〈0.05）.Conclusion： Jiawei Sanxiang Decoctioncan effectively treat intestinal qi stagnation and spleen deficiency type of functional constipation and can improve the TCM syn -dromes and relieve anxiety of patients .