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胎盘缺血性疾病临床流行病学研究进展 被引量:8

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摘要 胎盘缺血性疾病(ischemic placental disease)被认为是妊娠期持续的胎盘缺血性综合征,是导致早产的主要因素,包括子痫前期、胎儿生长受限(fetal growth restriction,FGR)/小于胎龄儿(small for gestational age,SGA)及胎盘早剥这3种疾病[1]。尽管几种疾病临床表现多种多样,但是其共同的病理生理基础是多种原因导致的妊娠早期子宫螺旋小动脉重铸障碍和胎盘滋养细胞侵袭能力下降,进而发生子宫胎盘血液循环障碍和胎盘功能缺陷,导致持续性胎盘缺氧而释放大量因子入血,最终在各个疾病进程中引发各种不同的临床表现[2]。本文旨在阐述其共同的病理生理基础及其目前临床流行病学研究进展。
作者 孙毅 李笑天
出处 《中华围产医学杂志》 CAS CSCD 2015年第6期421-424,共4页 Chinese Journal of Perinatal Medicine
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参考文献25

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共引文献32

同被引文献43

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