常规放疗治疗鼻咽癌中肿瘤退缩速度对患者预后的影响

Effect of tumor regression speed on prognosis of patients with nasopharyngeal carcinoma undergoing conventional radiotherapy

目的 探究鼻咽癌患者行常规放疗时,其肿瘤退缩速度对预后效果的影响.方法 选择76例鼻咽癌患者,为其实施常规放疗治疗.放疗完成后,对患者的生存情况实施随访调查.比较不同退缩速度的患者在预后效果方面的差异.结果 76例患者中,快速退缩、缓慢退缩、肿瘤残留患者的5年总生存率分别为63.64％（7/11）、76.32％（29/38）、48.15％（13/27）.快速退缩者5年无病生存及无远处转移生存率分别为54.55％、72.73％,缓慢退缩者为73.68％、81.58％,肿瘤残留者分别为33.33％、51.85％.结论 鼻咽癌患者行常规放疗时,肿瘤缓慢退缩、快速退缩、残留者的生存率逐次递减.

Objective To explore effect of tumor regression speed on prognosis of patients with nasopharyngeal carcinoma undergoing conventional radiotherapy.Methods 76 cases of nasopharyngeal carcinoma underwent conventional radiotherapy.After completion of radiotherapy,there was a followup investigation on patients＇ survival.Compared prognosis of patients with different tumor regression speeds.Results Among 76 patients,overall survival rates in 5 years of patients with rapid tumor regression speed,slow tumor regression speed and residual tumor were 63.64% （7/11）,76.32% （29/38） and 48.15% （13/27） respectively.Rates of disease-free survival and distant metastasis-free survival in 5 years of patients with rapid tumor regression speed were 54.55%,72.73%,those of patients with slow tumor regression speed were 73.68%,81.58%,those of patients with residual tumor were 33.33%,51.85%.Conclusion Survival rate of nasopharyngeal carcinoma patients undergoing conventional radiotherapy with slow tumor regression speed,rapid tumor regression speed and residual tumor gradually decreased.