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LCT与HR-HPV DNA在预测LEEP术治疗宫颈上皮内瘤变后复发中的作用 被引量:5

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摘要 目的探讨液基细胞学检查(LCT)与高危型HPV DNA在LEEP术治疗宫颈上皮内瘤变后的随访复查时的作用。方法选择行LEEP术的CINⅡ-Ⅲ级患者共1 845例,随访2年,行LCT、高危HPV DNA(HR-HPV DNA)等检查,收集患者的临床资料,评价各种方法及因素在LEEP术治疗CIN后复发的预测价值。结果对1 845例患者进行了24个月随访,其中35例患者失访,失访率为1.89%,对1 810例患者统计发现复发患者142例,复发率为7.85%。LCT与HR-HPV DNA分别用于判断LEEP术后复发获得了较高的敏感度、特异性及约登指数,但采用LCT+HR-HPV DNA则预测价值更高,敏感度达0.866,特异性为0.949,约登指数为0.815。结论联合应用LCT和HRHPV DNA对在LEEP治疗的复发随访中具有更高的指导价值,值得临床推广。
出处 《现代中西医结合杂志》 CAS 2015年第17期1872-1874,共3页 Modern Journal of Integrated Traditional Chinese and Western Medicine
基金 上海市第七人民医院重点学科建设资助项目(XK2013-01)
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参考文献8

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同被引文献45

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