多导睡眠监测仪在老年阻塞性睡眠呼吸暂停综合征中的应用

Application of Polysomnograph in Aged Patients with Obstructive Sleep Apnea Syndrome

目的分析多导睡眠监测仪在老年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)中的应用价值。方法收集2012年2月—2014年3月期间OSAHS的老年患者150例,作为OSAHS组。OSAHS患者又根据病情轻重分为轻、中、重组,纳入同时期健康志愿者50例作为对照组。采用多导睡眠监测仪对所有受试者进行睡眠监测,观察指标为AHI、LSAT、MAI、Sa O2<90%T,比较组间差异。结果老年OSAHS组患者AHI和MAI显著高于对照组,LSAT显著低于对照组,Sa O2<90%T值则显著长于对照组,P<0.05。LSAT与AHI呈负相关(r=-0.569,P<0.05);MAI、Sa O2<90%T与AHI呈正相关(r分别为0.569和0.697,P<0.05)。结论多导睡眠监测仪能有效检测老年OSAHS,LSAT、MAI、Sa O2<90%T与AHI呈相关性,能用于OSAHS病情的辅助判断。

Objective To study the values of applying polysomnograph in aged patients with obstructive sleep apnea syndrome （OSAHS）. Methods We enrolled 150 aged patients with OSAHS as the OSAHS group. According to the severity of OSAHS, these patients were further stratified in group of mild, moderate, and sever. Fifty healthy volunteers were enrolled as the control group. All subjects underwent sleep monitoring by using polysomnograph. Polysomnographic variables assessed among study groups included Apnea/Hypopnea index （AHI）, lowest oxygen saturation （LSAT）, mixed apnea index （MAI）, and the time of oxygen saturation of less than 90%（SaO2〈90%T）. Results Compared to the control subjects, the OSAHS patients presented with significantly increased AHI and MAI, decreased LSAT, and prolonged SaO2〈90%T values （P 〈 0.05, all four parameters）. AHI was negatively correlated with LSAT （r=-0.569,P〈0.05） and positivity correlated with MAI and SaO2〈90%T （r=0.569 and 0.697, respectively,P〈 0.05）. Conclusions Polysomnograph can effectively test OSAHS for aged patients, indicating correlations between LSAT,MAI, SaO2〈90%T and AHI, and assisting the assessment of OSAHS severity.