孟鲁司特钠用于上呼吸道感染后出现咳嗽症状患儿的临床疗效分析

Analysis of the clinical efficacy in children with cough symptoms appear montelukast sodium used for upper respiratory tract infection

目的探讨孟鲁司特钠用于上呼吸道感染后出现咳嗽症状患儿的临床疗效。方法选择该院2012年9月—2014年9月上呼吸道感染后咳嗽不止的患儿186例,采用隐匿数字随机法分为两组,对照组93例给予镇咳祛痰药物,观察组在上述治疗的同时加服孟鲁司特钠,动态观察症状改善情况,并评价疗效。结果治疗后6 d、9 d两组咳嗽评分明显低于治疗前(P<0.05),观察组咳嗽评分降低幅度明显大于对照组(P<0.05)。观察组总有效率92.47%,明显高于对照组(P<0.05)。观察组平均咳嗽缓解时间、平均治疗时间短于对照组,9 d症状改善率高于对照组,组间比较,差异有统计学意义(P<0.05)。结论镇咳祛痰药物治疗的同时辅以孟鲁司特钠治疗小儿上呼吸道感染后咳嗽,可明显缩短咳嗽时间和疗程,症状改善明显,有临床应用价值。

Objective Clinical curative effect in children with cough symptoms appear observation of montelukast sodium used for upper respiratory tract infection. Methods In our hospital in 2012 September-2014 September 186 cases of children with cough in with upper respiratory tract infection in with occult after, randomly divided into two groups,93 cases in the control group were given the antitussive and expectorant drugs,the observation group in the above treatment at the same time served plus montelukast sodium, dynamic observation of symptoms to improve the situation, and evaluation of curative effect. Results After the treatment, two groups of cough in 6D,9D score was significantly lower than that before the treatment （P〈0.05）, the observation group cough score significantly higher than that of control group （P〈0.05）. Total efficiency of the observation group was 92.47%, significantly higher than the control group （P〈0.05）.The observation group average cough relief time, average period of treatment is shorter than that in control group, 9D symptom improvement rate was higher than the control group. The comparison between groups （P〈0.05）. Conclusion drugs for eliminating phlegm antitussive and with the assistance of montelukast sodium in treatment of children with upper respiratory tract infection of cough, cough can shorten the time and period of treatment, symptoms improved significantly, with the value of clinical application.