藤梨正丁醇部位化学成分的研究

Study on chemical compound of n-butyl alcohol fraction fromActinidia arguta(Sieb.& Zucc)Planch.ex Miq.

采用薄层色谱,正相、反相硅胶,葡聚糖凝胶,半制备高效液相柱对中药藤梨的正丁醇部位进行了分离研究.得到8个化合物,分别为:2-β-D-葡萄糖-1,3,7-三羟基-酮(1),7-O-[β-D-吡喃木糖-(1-6)-β-D-吡喃葡萄糖苷]-1,8-二羟基-3-甲氧基-酮(2),3-O-[β-D-吡喃鼠李糖-(1-6)-β-D-吡喃葡萄糖]-5,7,4′-三羟基黄酮(3),6-C-葡萄糖-5,7,3′,4′-四羟基黄酮(4),6-C-葡萄糖-5,7,4′-三羟基黄酮(5),1-O-[β-D-吡喃木糖-(1-6)-β-D-吡喃葡萄糖苷]-8-羟基-3,7-二甲氧基-酮(6),3-O-[β-D-吡喃鼠李糖-(1-6)-β-D-吡喃半乳糖]-5,7,3′,4′-四羟基黄酮(7),7-O-[β-D-吡喃鼠李糖-(1-6)-β-D-吡喃葡萄糖]-5,3′-二羟基-4′-甲氧基二氢黄酮(8).所有的化合物都是首次从该植物分离得到.

To study chemical composition of fraction from Actinidia arguta （Sieb. ＆ Zucc） Planch. ex Miq. TLC, normal-phase silica gel column, reverse-phase silica gel column, sephadex-LH and semi-preparative HPLC column were used to isolate chemical compositions of n-butyl alcohol fraction from arguta （Sieb. ＆ Zucc） Planch. ex Miq. Eight compounds were identified as ： 2-β-D-Glu 1,3,7-tri hydrogen-xanthone （1）, 7-O- [ beta-D-xylose-（ 1-6 ）-beta D-glucopyranoside ]-1, 8-dihydroxy-3-methoxy Xanthone （2） ; 3-O-[-beta-D-Pyranrham-nose-（ 1-6 ）-beta-D-galactopyranose ]-5, 7, 4＇-trihydroxy flavone （3） ; 6-C-glucose-5,7,3＇, 4＇-tetra hydroxy flavone （4） ; 6-C-glucose -5,7,4＇-tri- hydroxy flavone（5）, 1-O-[beta-D-xylose-（ 1-6）-beta-D-glucopyranoside]-8-hydroxy-3,7- dimethoxy Xanthone （6） ; 3-O-[-beta-D-pyran rhamnose-（1-beta-D-pyran galactose]-5, 7,3＇ ,4＇-tetrahydroxy flavone （7） ; 7-O-[-beta-D-pyran rhamnose-（1-6）-beta-D-pyran glu- cose]-5, 3＇-dihydroxy-4＇-methoxy two dihydrogen flavone （8）. All compounds were iso- lated for the first time from this plant, moreover, all compounds were gained from genus for first time.