C反应蛋白联合白细胞检测在小儿风热乳蛾中的临床意义

Clinical value of combined detection of C-reactive protein and white blood cell in children with anemopyretic tonsillitis

目的探讨C反应蛋白(CRP)联合白细胞检测在小儿风热乳蛾中的临床意义。方法选择该院284例诊断为风热乳蛾患儿为研究对象,分为胃火炽盛组131例,风热外侵组153例,另将120例健康儿童纳入健康对照组。分析各组的白细胞计数、中性粒细胞百分比(NEU%)、淋巴细胞百分比(LYM%)与CRP。结果胃火炽盛组及风热外侵组患儿的白细胞、NEU%均高于健康对照组(P<0.05),风热外侵组患儿的CRP高于胃火炽盛组和健康对照组(P<0.05),胃火炽盛组患儿的CRP高于健康对照组(P<0.05);风热外侵组CRP的Cut-off值为12.65mg/L时,灵敏度为90.6%,特异度为86.3%。结论白细胞和CRP联合检测对风热乳蛾的分型诊断有一定临床价值。

Objective To explore the clinical significance of combined detection of C‐reactive protein （CRP）and white blood cells （WBC）in children with anemopyretic tonsillitis .Methods A total of 284 patients with anemopyretic tonsillitis were divided into ex‐cessive pattern group （131 cases） ,wind‐heat invasion group （153 cases） ,other 120 healthy children were recruited into control group .The WBC ,percentage of neutrophils （NEU % ） ,percentage of lymphocytes （LYM % ） and CRP were analyzed among the three groups .Results WBC and NEU% in excessive pattern group and wind‐heat invasion groups were higher than those in the control group （P〈 0 .05） ,CRP in wind‐heat invasion group was higher than that in excessive pattern group and the control group （P〈 0 .05） .CRP in the excessive pattern group were higher than that in the control group （P〈 0 .05） .When CRP cut‐off value in wind‐heat invasion group was 12 .65 mg/L ,the sensitivity was 90 .6% ,specificity was 86 .3% .Conclusion The combined detection of WBC and CRP have clinical value in differential diagnosis of children with anemopyretic tonsillitis .