急性脑梗死患者血清同型半胱氨酸检测的意义

Value of homocysteine in patients with acute cerebral infarction

目的研究同型半胱氨酸(Hcy)检测对急性脑梗死患者的预防、治疗及诊断的临床意义。方法 2012年8月至2014年10月该院收治的急性脑梗死患者88例纳入研究组,同期该院体检健康者50例纳入对照组,所有被试均采取酶循环法进行Hcy检测并进行比较。结果治疗前、后研究组患者的Hcy水平均明显高于对照组,研究组治疗后Hcy水平明显低于治疗前,差异均有统计学意义(P<0.05)。研究组42.27%的患者出现高同型半胱氨酸血症,明显高于对照组的14.00%,差异有统计学意义(P<0.05)。结论急性脑梗死的患者Hcy水平与病情密切相关,检测Hcy水平能够为急性脑梗死的诊断与治疗提供有效的观察指标。

Objective To study value of homocysteine （Hcy） in patients with acute cerebral infarction for prevention ,early diag‐nosis and treatment .Methods A total of 88 patients with acute cerebral infarction from August 2012 to October 2014 were collect‐ed in study group ,50 healthy persons were recruited in control group .Enzyme cycle method was used to measure levels of Hcy in the study group before and after treatment and the control group .Results The levels of Hcy in the study group before and after treatment were significant higher than that of the control group ,the level of Hcy in the study group after treatment were significant lower than that before treatment ,the differences had statistical significance（P 〈 0 .05） .There was 42 .27% patients in the study group had hyper‐homocysteinemia ,which was significant higher than 14 .00% in the control group （P〈 0 .05） .Conclusion For pa‐tients with acute cerebral infarction ,Hcy levels are closely correlated with their condition ,detection of Hcy could provide effective measure for diagnosis and treatment of acute cerebral infarction .