国内外Q-TOF在环境监测上的应用

Application of QTOF on environmental monitoring

当前,环境污染物质的生态和健康影响正引起越来越多的关注。环境应急监测需要在保证数据质量的前提下,快速、准确地出具数据,重点在于快速与准确。但环境污染事故中的污染物质种类多样,很多污染物甚至连实验室方法都未曾建立。因此,未知化合物的定性尤为重要。本文调查和整理了国内外TOF和Q-TOF/MS用于环境污染物质的分析测定,通过比较目前广泛用于环境污染物鉴定的质谱技术的优缺点,以及国内外的研究成果,重点讨论了飞行时间质谱仪(QTOF)技术在环境污染物鉴定方面的巨大优势。Q-TOF的突破和发展将在环境监测分析领域中发挥重要作用。

Environmental contaminants ecological and health effects are causing growing concern. They in- clude pharmaceuticals, personal care products, pesticides and disinfectants, among others. The aim of this study was to survey the application of emerging contaminants and priority substances monitoring on the use of time-of- flight mass spectrometry（TOF MS） and quadrupole time-of-flight mass spectrometry（Q-TOF MS）. Thanks to the accurate-mass full-spectrum acquisition in TOF MS and Q-TOF MS, it was feasible to widen the number of com- pounds to be investigated to other families of contaminants. This allowed the detection of emerging contaminants, such as pesticides and its metabolites, natural products, among others. In this review, we focus on the importance of unequivocally detecting emerging contaminants by accurate mass spectrometric measurement technioues.