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Understanding diabetic retinopathy 被引量:1

Understanding diabetic retinopathy
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摘要 A recent survey shows that diabetes affect 92.4 million people in China's Mainland[1],among which 16.9 million have diabetic retinopathy(DR)[2].DR is one of the major causes of blindness in the working age population in A recent survey shows that diabetes affect 92.4 million people in China's Mainland [1], among which 16.9 million have diabetic retinopathy (DR) [2]. DR is one of the major causes of blindness in the working age population in both developing and developed countries. Although the exact mechanism by which diabetes causes retinopathy remains elusive, several hypotheses have been postulated to explain pathogenies of the disease. Here we invited five groups of scientists and clinicians to share their recent discoveries and expert opinions in molecular biology, pathophysiology, genetics, and epigenetics of DR.
作者 PU MingLiang
机构地区 Department of Anatomy
出处 《Science China(Life Sciences)》 SCIE CAS CSCD 2015年第6期519-520,共2页 中国科学(生命科学英文版)
基金 supported by grants from National Basic Research Program of China(973 Program,2011CB510206)
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  • 1Hiroaki Itamochi.Targeted therapies in epithelial ovarian cancer: Molecular mechanisms of action[J].World Journal of Biological Chemistry,2010,1(7):209-220. 被引量:14
  • 2Osborne NN, Casson RJ, Wood JPM, Chidlow G, Graham M, Melena J. Retinal ischemia: mechanisms of damage and potential therapeutic strategies. Prog Retin Eye Res, 2004, 23: 91-147.
  • 3Buchi ER. Cell death in the rat retina after a pressure-induced ischaemia-reperfusion insult: an electron microscopic study. I. Ganglion cell layer and inner nuclear layer. Exp Eye Res, 1992, 55: 605-613.
  • 4Lafuente MP, Villegas-Perez MP, Selles-Navarro I, MayorTorroglosa S, de Imperial JM, Vidal-Sanz M. Retinal ganglion cell death after acute retinal ischemia is an ongoing process whose severity and duration depends on the duration of the insult. Neuroscience, 2002, 109: 157-168.
  • 5Nucci C, Tartaglione R, Rombola L, Morrone LA, Fazzi E, Bagetta G. Neurochemical evidence to implicate elevated glutamate in the mechanisms of high intraocular pressure (IOP)-induced retinal ganglion cell death in rat. Neurotoxicology, 2005, 26: 935-941.
  • 6Yamamoto H, Schmidt-Kastner R, Hamasaki DI, Yamamoto H, Parel JM. Complex neurodegeneration in retina following moderate ischemia induced by bilateral common carotid artery occlusion in Wistar rats. Exp Eye Res, 2006, 82: 767-779.
  • 7Bringmann A, Francke M, Pannicke T, Biedermann B, Faude F, Enzmann V, Wiedemann P, Reichelt W, Reichenbach A. Human Muller glial cells: altered potassium channel activity in proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci, 1999,40: 3316-3323.
  • 8Kim lB, Kim KY, Joo CK, Lee MY, Oh SJ, Chung JW, Chun MH. Reaction of Muller cells after increased intraocular pressure in the rat retina. Exp Brain Res, 1998, 121: 419-424.
  • 9Da T, Verkman AS. Aquaporin-4 gene disruption in mice protects against impaired retinal function and cell death after ischemia. Invest Ophthalmol Vis Sci, 2004, 45: 4477-4483.
  • 10Yanoff M, Fine BS, Brucker AJ, Eagle Jr. Ralph C. Pathology of human cystoid macular edema. Surv Ophthalmol, 1984, 28(Suppl): 505-511.

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