摘要
The known complexity of eukaryotic transcriptomes has been greatly expanded due to the identification of a large family of circular RNAs in recent years [1-3]. As a special form of RNA compared to the "common" linear form, these molecules were first described in 1976, when it was discov- ered that several plant viroids were single-stranded and co- valently closed circular RNAs [4].
The known complexity of eukaryotic transcriptomes has been greatly expanded due to the identification of a large family of circular RNAs in recent years[1?3].As a special form of RNA compared to the"common"linear form,these molecules were first described in 1976,when it was discovered that several plant viroids were single-stranded and covalently closed circular RNAs[4].In a broad sense。