地奥司明片对混合痔术后水肿患者创面愈合影响的临床研究

Research on the Effect of Wound Healing for Treating Mixed Hemorrhoid Postoperative Edema Patients with Diosmin Tablets

目的分析地奥司明片治疗混合痔术后水肿的临床效果,并探究其对患者创面愈合的影响。方法选取2012年4月—2014年10月来该院就诊的74例混合痔术后水肿患者,随机分为对照组和观察组各37例。对照组患者单纯采用术后常规抗生素消炎、止血剂等治疗;观察组患者则在此基础上于术后第1日起给予地奥司明片口服治疗。观察患者术后水肿症状的改善情况,并对证候给予评分、用疼痛视觉模拟评分VAS评估患者的创面疼痛程度,计算创面愈合率。结果经治疗后水肿有所改善,证候积分逐渐下降,以观察组下降幅度更大(P<0.05)。两组患者经治疗后痛感较治疗前明显缓解,VAS评分较治疗前下降明显,观察组的变化较对照组突出(P<0.05);观察组患者的创面愈合率明显高于对照组患者(P<0.05)。结论地奥司明片治疗混合痔术后水肿疗效确切,能有效缓解创面疼痛,利于创面愈合,值得临床推广运用。

Objective To investigate the clinical efficacy of treating mixed hemorrhoidposto perative edema patients with diosmin tablets, and explore the effect of wound healing. Methods Choose from 2012 Aprit to 2014 October in Our hospital for treatment of 74 cases mixed hemorrhoid postoperative edema patients were randomly divided into a control group of 37 cases and an observa-tion group of 37 cases. Patients in the control group were treated with antibiotic antiphlogistic and hemostatic agent;while patients in the observation group were treated with diosmin tablets. We observed the improvement of clinical symptomsafter surgery, and e-valuated the change of symptoms score in pretherapy and post-treatment.We evaluated the pain with the VAS score, and calculat-ed the rate of wound healing. Results Theedema were improved clearly after treatment, and the symptom scores went down clearly, the degree of change in the observation group was more pronounced （P〈0.05）;The pain of the patients was relieved after treatment, and the VAS score declined clearly, the degree of change in the observation group was more pronounced （P〈0.05）;Therate of wound healing of the observation group was higher than that of the control group （P〈0.05）. Conclusion Treating mixed hemor-rhoidposto perative edema patients with diosmin tablets has definite curative effect,can relieve the pain, speed up the wound heal-ing, which is worthy of further research and development.