依达拉奉联合奥扎格雷治疗急性脑梗死的疗效分析

Analysis of therapeutic effect of edaravone combined with ozagrel in treatment of acute cerebral infarction

目的研究依达拉奉联合奥扎格雷治疗急性脑梗死的疗效。方法选取该院2012年1月—2014年10月间诊治的急性脑梗死患者120例,将其随机分为观察组和对照组各60例,对观察组患者采用依达拉奉联合奥扎格雷治疗,对对照组患者进行单纯的依达拉奉治疗,对比观察两组患者的临床治疗效果及C反应蛋白水平。结果观察组患者中,痊愈的患者为27例,显效的患者为21例,有效的患者为7例,无效的患者为5例,总有效率为91.67%,对照组患者中,痊愈的患者为11例,显效的患者为26例,有效的患者为12例,无效的患者为11例,总有效率为81.67%,观察组明显高于对照组,两组对比,差异有统计学意义(P<0.05);在C反应蛋白水平方面,观察组患者在治疗后为(7.06±1.43)mg/L,对照组患者在治疗后为(4.06±1.71)mg/L,观察组的下降水平明显高于对照组患者的水平,两组差异有统计学意义(P<0.05)。结论采用依达拉奉联合奥扎格雷治疗急性脑梗死不仅可以提高临床治疗效果,而且能够大大降低C反应蛋白水平,值得临床推广使用。

Objective To study the therapeutic effect of edaravone combined with ozagrel in treatment of acute cerebral infarction. Methods Selected 120 patients with acute cerebral infarction in our hospital and randomly divided into observation group and control group with 60 cases in each group.The observation group were treated by edaravone combined with ozagrel treatment ,the control group patients were given edaravone treatment alone. Compared two groups of clinical therapeutic effect and the level of C-reactive protein. Results The total effective rate of observation group was 91.67%,the control group the total effective rate was 81.67%,the observation group was significantly higher than that in the control group,with significant difference （P〈0.05）;C reac-tion protein of the observation group after treatment was （7.06±1.43）,which of the control group was （4.06±1.71）,the decreased level of the observation group was significantly higher than the control group levels,with statistically significant difference （P 〈0.05）. Conclusion The use of edaravone combined with ozagrel in treating acute cerebral infarction can not only improve the clini-cal treatment effect,but also can greatly reduce the level of C reactive protein,is worthy of clinical use.