弥漫性结缔组织病合并甲状腺功能异常96例临床疗效分析

96 Cases of Clinical Curative Effect Observation to Diffuse Connective Tissue Disease Merged Thyroid Dysfunction

目的探讨弥漫性结缔组织病合并甲状腺功能异常患者的临床治疗效果,为临床治疗提供依据。方法选取2010年10月—2014年8月收治的具有弥漫性结缔组织病合并甲状腺功能异常患者192例,随机分为对照组和治疗组各96例,对照组应用醋酸泼尼松片治疗,治疗组在应用醋酸泼尼松片治疗的基础上,联合甲状腺片或丙硫氧嘧啶治疗,进行疗效比较观察。结果治疗组甲状腺机能减退和甲状腺机能亢进患者FT3:(5.24±2.26);FT(4:20.64±10.33);对照组甲状腺机能减退患者FT3:(4.15±2.67);FT4:(17.22±8.51);甲状腺机能亢进患者FT3:(5.83±2.47);FT4:(23.26±9.54)。结论因此,根据患者的病情而选择合适的治疗方式,不仅可以有效地恢复FT3和FT4水平,而且可以明显地提高治疗效果,值得临床推广。

Objective To explore diffuse connective tissue disease clinical therapeutic effects of patients with thyroid dysfunction, provide the basis for clinical treatment.Methods Selection with diffuse connective tissue disease with thyroid dysfunction 192 patients in our hospital from 2010 October to 2014 August were randomly divided into control group and treatment group, the control group used prednisone acetate tablets treatment, the treatment group used prednisone acetate tablets, thyroid or propylthiouracil, compared the curative effect observation.Results The treatment group patients with hypothyroidism and hyperthyroidism FT3：（5.24±2.26）;FT4：（20.64±10.33）;The control group patients with hypothyroidism FT3：（4.15±2.67）;FT4：（17.22±8.51）;hyperthyroidism FT3：5.83±2.47;FT4：（23.26±9.54）.Conclusion According to the patient choose the right means of treatment, not only can effectively restore free T3 （FT3） and free T4 （FT4） levels, but also can significantly improve the treatment effect, worth clinical promotion.