104例新生儿败血症的临床治疗分析

Analysis of clinical treatment of 104 cases of neonatal septicemia

目的对新生儿败血症的临床诊断与治疗进行探究。方法对该院于2013年9月—2014年10月收治的104例血培养阳性患儿作为研究对象,对临床资料进行回顾性分析。结果该组患者在经过治疗之后,治愈78例,自动出院22例,死亡4例。治愈率为75.0%;此外,104例患者在经过治疗之后,并发症发生几率减小,其中包括电解质紊乱11例,硬肿症7例,皮肤炎症5例、肺炎2例,不良反应发生率为2.40%;血培养结果中以病原菌以及葡萄球菌为主,占据51%,且病原菌敏感的抗生素主要包括头孢唑啉、头孢哌酮、环丙沙星。结论临床中根据新生儿病史、体征以及药敏结果选取合适抗生素与治疗方法对新生儿败血症有效。

Objective clinical diagnosis and treatment of neonatal septicemia inquiry. Methods 104 cases of children with positive as the object of study of blood to our hospital from 2013 September to 2014 October were cultured, the clinical data were retrospectively analyzed. Results neonatal sepsis in the clinical manifestations are not specific, the probability of complications, the mortality rate is high, clinical blood culture as the main means to diagnose, pathogenic bacteria and Staphylococcus aureus in 51.0%, there were 19 cases of Staphylococcus epidermidis, Staphylococcus aureus in 12 cases, 7 cases of hemolytic staphylococci, 3 cases of Escherichia coli, Klebsiella pneumoniae in 2 cases. At present, the clinical antibiotics as the main treatment, mainly including cefazolin, ciprofloxacin, cefoperazone etc.Conclusion the clinical characteristics of children according to the causative agent and sensitive results, on the use of antibiotics to control, can reduce the complication rate and reduce the mortality rate.