试论原发性血小板减小性紫癜血液学诊断

On Idiopathic Thrombocytopenic Purpura Diagnosis of Blood

目的对原发性血小板减少性紫癜的诊断方式以及效果进行调查。方法选取该院2012年6月—2014年6月间23例原发性血小板减少性紫癜患者,同时选取该院同期来院体检的25例健康患者作为研究对象。对所有调查人员的血象以及血小板情况进行调查。结果疾病组患者的血小板平均直径为(5.12±0.38)μm;健康组血小板直径平均为(2.67±0.28)μm,两组比较,P<0.05。疾病组患者血小板体积平均为(26.5±7.4)μm3;健康组平均血小板体积为(8.3±2.2)μm3。对两组调查人员的血小板抗相关体阳性率进行调查:疾病组患者GMPⅡb抗体阳性率为52.2%,对照组为12%;疾病组患者GMPⅢ1a阳性率为60.9%,健康组为8%;疾病组患者GMP1b阳性率为47.8%,健康组为4%,两组调查人员比较P值均<0.05。疾病组患者血小板计数、血清结合珠蛋白水平明显低于健康组,两组比较P<0.05。结论血小板检测能够对原发性血小板减少性紫癜患者的诊断起到辅助作用,是一种有效的检测方式。

Objective To primary platelet investigation reduce diagnostic way purpura and the effect. Methods Selected in our hospital in 2012 June-2014 year in June 23 cases of idiopathic thrombocytopenic purpura patients, also selected 25 patients in our hospital health examination in the hospital at the same time as the research object. Investigation on Hemogram of all investigators and platelet. Results The mean platelet diameter disease group patients was （5.12±0.38）μm;platelet health group average diameter was （2.67±0.28）μm, two group of comparison, P 〈0.05. Disease patients of mean platelet volume was （26.5±7.4）μm3 health group;mean platelet volume was （8.3±2.2）μm3. On two groups of investigators, the positive rate of anti platelet associated body are investigated：the positive rate of B antibody in patients with GMP disease group II was 52.2%, 12%in the control group;group GMP III disease patients with 1A positive rate was 60.9%, the healthy group was 8%;the positive rate in patients with GMP1b disease group 47.8%, group 4%, group two the investigators compared P〈0.05. Disease patients with platelet count, serum haptoglobin levels were significantly lower than in the healthy group, P〈compared two groups of 0.05. Conclusion The detection of platelet to primary platelet auxiliary effect to reduce the diagnosis of purpura patients, is an effective detection method.