MS合并OSAS时血脂的变化和意义

CHANGES AND SIGNIFICANCE OF BLOOD LIPID IN MS COMBINED OSAS PATIENTS

目的:探讨代谢综合征(MS)合并阻塞性睡眠呼吸暂停低通气综合征(OSAS)时血脂的改变和意义。方法:以就诊于承德医学院附属医院的MS患者为研究对象,均行睡眠监测,其中单纯MS患者200例,MS合并OSAS患者265例。分别检测两组患者的体重指数(BMI)、颈围、腰围、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)和Epworth睡眠评价量表(ESS)评分。结果:MS+OSAS组患者的BMI、颈围、腰围、TG、TC、LDL-C明显高于MS组,HDL-C明显低于MS组(P<0.05)。MS+OSAS组患者,随着阻塞程度的加重,ESS评分逐渐升高(P<0.05)。结论:MS合并OSAS时可进一步加重血脂的改变;ESS评分可反映OSAS严重程度,积极治疗OSAS亦是预防心血管疾病的重要环节。

Objective： To investigate the changes and significance of blood lipid in metabolic syndromes （MS） combined obstructive sleep apnea hypopnea syndrome （OSAS） patients.Methods： The body weight index （BMI）, neck circumference, waist circumference, triglyceride （TG）, total cholesterol （TC）, high-density lipoprotein （HDL-C）, low density lipoprotein （LDL-C） and ESS score of 200 MS patients and 265 MS＋OSAS patients that were treated in the Afifliated Hospital of Chengde Medical College and monitored by polysomnography were measured and recorded respectively. Results：The BMI, neck circumference, waist circumference, TG, TC and LDL-C of MS＋OSAS patients were obviously higher than MS patients （P〈0.05）; but HDL-C was obviously lower （P〈0.05）. For MS＋OSAS patients, the ESS score gradually increased as the degree of obstruction.Conclusions： MS combined OSAS can increase the changes of blood lipid;ESS score may relfect the severity of OSAS, active treatment of OSAS is also an important part for preventing cardiovascular disease.