摘要
单胺类神经递质及其转运体水平异常无法全面解释抑郁症的发病机制,抗抑郁药治疗的疗效特点说明,单胺类神经递质及其转运体异常仅为抑郁症病理机制的某个方面,可能存在其他影响抑郁症发病的机制。近年来,为更全面了解抑郁症的发病机制并更好地治疗抑郁症,抑郁症患者的神经形态学变化及神经可塑性研究引起了学者们的广泛关注。
Abnormal levels of monoamine neurotransmitters and their transporter cannot fully explain the pathogenesis of depression.The therapeutic characteristics of antidepressants indicate that abnormal mono-amine neurotransmitters and the transporters are only one aspect of pathological mechanism of depression,and there may be other mechanisms affecting depression.In recent years, the study of neural morphological chan-ges and neuronal plasticity of patients with depression has caused wide attention of the scholars in the effort of finding a more complete understanding of the pathogenesis and better treatment of depression .
出处
《医学综述》
2015年第10期1802-1804,共3页
Medical Recapitulate
关键词
抑郁症
神经形态变化
可塑性假说
Depression
Morphological changes
Plasticity hypothesis
