期刊文献+

肿瘤大小在pT4aN0M0期胃癌患者预后中的价值

下载PDF
导出
摘要 目的探讨肿瘤大小对p T4a N0M0期胃癌患者预后的影响。方法收集170例行胃癌根治性且有术后病理诊断为p T4a N0M0期的胃癌患者的临床资料,比较不同临界值下肿瘤最大径较小患者和肿瘤最大径较大患者的生存率。并且分析肿瘤大小与其他临床病理特征的相关性。患者出院后通过电话随访、门诊记录或邮件获得患者的生存期等随访信息并进行生存分析。结果所有患者的肿瘤最大径为0.5~18.0 cm,平均(5.2±0.4)cm。当区分肿瘤大小的临界值定为8 cm时,生存率的差异最显著。肿瘤最大径〈8 cm患者和肿瘤最大径≥8 cm患者之间在不同性别、肿瘤位置和手术切除类型方面差异有统计学意义。肿瘤最大径〈8 cm胃癌患者的术后生存率明显高于肿瘤最大径≥8 cm患者。结论肿瘤大小是p T4a N0M0期胃癌的独立预后因素。
出处 《广东医学》 CAS 北大核心 2015年第10期1559-1561,共3页 Guangdong Medical Journal
  • 相关文献

参考文献10

  • 1KAMANGAR F,DORES G M,ANDERSON W F.Patterns of cancer incidence,mortality,and prevalence across five continents:defining priorities to reduce cancer disparities in different geographic regions of the world[J].J Clin Oncol,2006,24(14):2137-2150.
  • 2陆俊,黄昌明,郑朝辉,李平,谢建伟,王家镔,林建贤.肿瘤大小对早期胃癌病人预后的影响[J].中国实用外科杂志,2012,32(9):758-761. 被引量:10
  • 3NOMURA E,LEE S W,TOKUHARA T,et al.Functional outcomes according to the size of the gastric remnant and the type of reconstruction following distal gastrectomy for gastric cancer:an investigation including total gastrectomy[J].Jpn J Clin Oncol,2013,43(12):1195-1202.
  • 4KUNISAKI C,MAKINO H,TAKAGAWA R,et al.Tumor diameter as a prognostic factor in patients with gastric cancer[J].Ann Surg Oncol,2008,15(7):1959-1967.
  • 5YOKOTA T,ISHIYAMA S,SAITO T,et al.Is tumor size a prognostic indicator for gastric carcinoma?[J].Anticancer Res,2002,22(6B):3673-3677.
  • 6JUN K H,JUNG H,BAEK J M,et al.Does tumor size have an impact on gastric cancer? A single institute experience[J].Lange-nbecks Arch Surg,2009,394(4):631-635.
  • 7BILICI A,UYGUN K,SEKER M,et al.The effect of tumor size on overall survival in patients with pT3 gastric cancer:Experiences from 3 centers[J].Onkologie,2010,33(12):676-682.
  • 8CHOI J,KIM SG,IM J P,et al.Endoscopic estimation of tumor size in early gastric cancer[J].Dig Dis Sci,2013,58(8):2329-2336.
  • 9LU J,HUANG C M,ZHENG C H,et al.Consideration of tumor size improves the accuracy of TNM predictions in patients with gastric cancer after curative gastrectomy[J].Surg Oncol,2013,22(3):167-171.
  • 10OTSUJI E,KURIU Y,ICHIKAWA D,et al.Time to death and pattern of death in recurrence following curative resection of gastric carcinoma:analysis based on depth of invasion[J].World J Surg,2004,28(9):866-869.

二级参考文献15

  • 1Yosuke Adachi, Kazuhiro Yasuda. Pathology and prognois of gastric carcinoma [J] .Cancer ,2000,89 (7): 1414-1424.
  • 2Ahmet Bilici, Kazim Uygunb, Mesut Seker, et al. The effect of tumor size on overall survival in patients with pT3 gastric cancer: Experiences from 3 centers [J]. Onkologie, 2010,33(12):676-682.
  • 3Otsuji E, Kuriu Y, Ichikawa D, et al. Prediction of lymph node metastasis by size of early gastric carcinoma [Jl. Hepatogastro- enterology,2007,54(74):602-605.
  • 4Youn HG, An JY, Choi MG, et al. Recurrence after curative re- section of early gastric cancer [J]. Ann Surg Oncol,2010,17(2):448-454.
  • 5Jun KH, Jung H, Baek JM, et al. Does tumor size have an impact on gastric cancer? A single institute experience [J]. Langen- becks Arch Surg, 2009,394(4):631-635.
  • 6Skoropada V, Berdov B, Zagrebinb V, et al. Clinicopathological features and outcome of surgical treatment of 149 patients with early (pT1) gastric cancer[J]. Onkologie, 2005, 28(5):247-252.
  • 7Piso P, Weber U, Benten D, et al. Early gastric cancer - excel- lent prognosis after curative resection in 87 patients irrespec- tive of submucosal infiltration, lymph-node metastases or tu- mor size [J ]. Langenbeck Arch Surg, 2001, 386(1):26-30.
  • 8Kunisaki C, Akiyama H, Nomura M, et al. Signi fi cance of Long-Term Follow-Up of Early Gastric Cancer [J]. Ann Surg Oncol, 2006, 13(3): 363-369.
  • 9Cheong JH, Hyung WJ, Shen JG, et al. The N ratio predicts re- currence and poor prognosis patients with node-positive early gastric cancer[J]. Ann Surg Oncol, 2006,13(3): 377-385.
  • 10Cao L, Hu X, Zhang Y,et al. Adverse prognosis of clus- tered-cell versus single-cell micrometastases in pN0 early gas- tric cancer[J]. J Surg Oncol, 2011,103(1):53-56.

共引文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部