参麦注射液对肺心病患者血流动力学和心功能的影响

The Influence of Shenmai Injection Treatment of Pulmonary Heart Disease on Heart Function and Blood Stream Dynamics

目的探讨参麦注射液对肺心病患者血流动力学和心功能的影响。方法 144例肺心病患者随机分为对照组(n=72)和观察组(n=72),对照组给予常规治疗,观察组在常规治疗基础上加用参麦注射液,14d为1个疗效,比较两组临床疗效。结果观察组总有效率显著高于对照组(94.45%VS 81.94%,P<0.05);两组患者全血黏度和红细胞黏度均有下降(P<0.05),但观察组下降幅度高于对照组(P<0.05);两组患者经治疗后,左心室收缩功能和舒张功能均有所改善(P<0.05),但观察组改善更为明显(P<0.05)。结论参麦注射液可改善肺心病患者血流动力学指标,改善心、肺功能,增强心脏收缩力,提高机体耐缺氧能力和抗应激能力,对患者预后具有重要价值。

OBJECTIVE To explore the influence of Shenmai injection treatment of pulmonary heart disease on heartfunctionandbloodstreamdynamics.METHODS 144casesofpulmonaryheartdiseaseweredividedintocon-trol group（n=72） and observation group（n=72）.Control group was treated with routine therapy,and observation group was treated with Shenmai injection on the basis of control group.After 14 days, the effect was com-pared.RESULTS The total effective rate in observation group was significantly higher than that in control group （94.45%VS 81.94%,P〈0.05）.Blood viscosity and packed cell viscosity had dropped significantly than that in observation group（P〈0.05）.The cardiac systolic and diastolic functions were improved in two groups（P〈0.05）, but observation group improved degree better than control group significantly（ P〈0.05）.CONCLUSION Shenmai injection can improve heart function and blood stream dynamics,and gain the good results on the prognosis of pulmo-nary heart disease.