温阳健脾化湿活血法治疗病毒性肝炎难治性黄疸疗效观察

Observe Curative Effect of Warming Yang Fortifying Spleen Resolving Dampness and Activating Blood Method on Treating Refractory Icteric Viral Hepatitis

目的:探讨温阳健脾化湿活血法治疗病毒肝炎难治性黄疸的临床疗效。方法:采用随机数字表法将本院2014年1月—2014年8月收治的80例病毒肝炎难治性黄疸患者分为中医组和单纯西医组各40例,单纯西医组采用西医常规疗法,中医组在此基础上采用中医温阳健脾化湿活血法治疗,两组患者均治疗3个月,比较两组患者治疗前后的临床疗效、肝功能及中医症候积分的变化差异。结果:治疗前中医组和单纯西医组的TBIL、ALT、AST、TBA、ALP、SCB、GGT检测值差异不具有统计学意义(P>0.05);治疗后两组患者的肝功能指标TBIL、ALT、AST、TBA、SCB、GGT较治疗前均显著的降低(P<0.05),中医组TBIL、ALT、AST、TBA、SCB显著低于单纯西医组(P<0.05)。治疗前中医组的中医证候身目黄染、脘痞腹胀、食欲不振、神疲乏力、蜘蛛痣、肝掌、舌淡红、舌腻积分与单纯西医组比较差异具有统计学意义(P>0.05);治疗后两组患者的身目黄染、脘痞腹胀、食欲不振、神疲乏力、蜘蛛痣、舌淡红、舌腻积分积分较治疗前均显著降低(P<0.05),且治疗后中医组各证候积分较单纯西医组显著降低(P<0.05)。中医组患者的总有效率为92.5%显著高于单纯西医组的75.00%,且差异具有统计学意义(P<0.05)。结论:中医温阳健脾化湿活血法治疗病毒肝炎难治性黄疸结合常规西医疗法能够显著改善患者肝功能,改善患者的中医证候,提高临床疗效。

Objective ： To investigate the clinical efficacy of warming yang fortifying spleen resolving dampness and activating blood method in treating refractory jaundice viral hepatitis. Methods ： The use of randomLy gO cases of viral hepatitis in our hospital from 2014 January to 2014 August were refractory jaundice patients were divided into traditional Chinese medicine group and Western medicine group with 40 cases in each group, western medicine group were treated with routine therapy, traditional Chinese medicine group based on the use of traditional Chinese medicine warming yang fortifying spleen resolving dampness and activating blood therapy, two groups of patients 3 months of treatment, clinical efficacy, change difference before and after treatment in two groups were compared with the liver function and traditional Chinese medicine syndrome integral. Results： Before treatment, traditional Chinese medicine group and Western medicine group of TBIL, ALT, AST, TBA, ALP, SCB, GGT detection of the value of the difference was not statistically significant （ P〉0.05 ）; the two groups after treatment in patients with liver function indexes of TBIL, ALT, AST, TBA, SCB, GGT compared with those before treatment were significantly decreased （ P〈0.05 ）, in TBIL, ALT, AST medical group, TBA, SCB were significantly lower than those of the simple western medicine group （P〈0.05）. The Chinese medicine group before treatment of traditional Chinese medicine syndrome of body jaundice, abdominal distension, loss of appetite and digestive tract infection, lassitude, spider angioma, liver palm, pink tongue, tongue greasy integral and simple western medicine group with significant difference （ P〉0.05 ）; the two groups after treatment patients with jaundice, epigastrie fullness, poor appetite, abdominal distension lassitude, spider mole, pink tongue, tongue greasy integration than before treatment were significantly decreased （ P〈0.05 ）, Chinese medicine syndrome group after treatment and integral compared with simple western medicine group decreased significantly （ P〈0.05 ）. The Chinese medicine group were 92.5% of total effective rate was significantly higher than that of simple western medicine group of 75% and the difference was statistically significant （ P〈0.05 ）. Conclusion ： Chinese medicine warming yang fortifying spleen resolving dampness and activating blood in treating refractory jaundice virus hepatitis combined with routine western medicine therapy can significantly improve the liver function, improve the traditional Chinese medicine syndrome of patients, improve the clinical efficacy.