病毒性肠炎合并惊厥的血盐水平及脑脊液生化检查研究

The Research of Blood Salt Levels and CSF Biochemical in Viral Enteritis Merger Combined with Convulsions

目的:探讨病毒性肠炎合并惊厥的血盐水平及脑脊液病毒生化检查结果。方法:回顾性分析本院2010年1月-2014年10月收治的病毒性肠炎合并惊厥患儿69例的临床资料,将惊厥可按照发作频率分为频繁性(>3次)惊厥组(22例)与非频繁性(<3次)惊厥组(47例),按性质分为良性惊厥(52例)与非良性惊厥(17例),比较频繁性惊厥与非频繁性惊厥、良性惊厥与非良性惊厥患儿的血盐水平及脑脊液病毒生化检查结果。结果:惊厥频繁患儿的低血钠、低血钾、低血钙、低血镁及脑脊液生化检查病毒阳性比例均显著高于惊厥非频繁患儿(P<0.05);良性惊厥患儿体温、惊厥发作次数、惊厥持续时间及大便轮状病毒检查阳性率均显著低于非良性惊厥患儿(P<0.05)。结论:病毒性肠炎合并惊厥患儿中频繁性惊厥伴有低血钠、低血钾、低血钙、低血镁症状及脑脊液病毒感染,良性惊厥患儿的体温、惊厥发作次数、惊厥持续时间及大便轮状病毒检查阳性率均要低于非良性惊厥。

Objective：To explore the blood salt levels and CSF biochemical in Viral enteritis combined with convulsions. Method：The clinical date of 69 children with viral enteritis merger and convulsions in our hospital from January 2010 to October 2014 were retrospectively analysed.They were divided into frequent seizures（≥3 times） group（22 patients） and non-frequent （〈3 times） seizures（47 cases） group according to the seizures frequency,according to the nature they were divided into benign convulsions （52 patients） and non-benign convulsions （17 patients）.Salt levels in blood and viral biochemical test results of cerebrospinal fluid were compared between Frequent seizures and non-frequent seizures,Benign convulsions and Non-benign convulsions.Result：Frequent seizures group were significantly higher than the non-frequent seizures group（P〈0.05） and the Benign convulsions group were significantly lower than the Non-benign convulsions group （P〈0.05） in the following aspects： The temperature, the number of seizures,duration of convulsions and the positive rate of rotavirus stool test in the Benign convulsions group were lower than that of the Non-benign convulsions group. Conclusion： Viral enteritis with frequent seizures convulsions is often accompanied by the symptoms of hyponatremia, hypokalemia, hypocalcemia, hypomagnesemia and viral infection of cerebrospinal fluid. The temperature, the number of seizures, duration of convulsions and the positive rate of rotavirus stool test in the Benign convulsions group were lower than that of the Non-benign convulsions group.