妊娠期亚临床甲状腺功能减退患者甲状腺激素治疗分析

The Treatment Analyze of Subclinical Hypothyroidism Patients in Gestation Period by Thyroid Hormones

目的:探讨妊娠期亚临床甲状腺功能减退患者甲状腺激素治疗效果情况。方法:分析本院2012年8月-2014年8月收治的妊娠期亚临床甲状腺功能减退患者34例临床资料,依据是否进行甲状腺激素治疗进行分组,未治疗组14例和治疗组20例。结果:治疗组TSH、血清甘油三酯、总胆固醇异常均低于未治疗组,FT3、FT4水平均高于未治疗组,治疗组早产、妊娠期高血压疾病、子痫前期、胎盘早剥和妊娠期贫血发生率均低于未治疗组,两组比较差异均有统计学意义(P<0.05)。结论:妊娠期亚临床甲状腺功能减退患者甲状腺激素治疗可以提高妊娠结局,降低妊娠并发症,值得临床推广应用。

Objective：To approach the treatment result of subclinical hypothyroidism patients in gestation period by thyroid hormones.Method：34 patients clinical data of subclinical hypothyroidism in gestation period were selected in our hospital from August 2012 to August 2014,and were divided into two groups,no treatment group of 14 cases and treatment group of 20 cases.Result：The TSH,TG,total cholesterol abnormalities of treatment group were better than no treatment group,FT3,FT4 level were higher than no treatment group,the premature delivery,pregnancy-induced hypertension,preeclampsia,abruptio placentae and incidence of anemia during pregnancy of treatment group were lower than no treatment group,the differences were statistically significant（P〈0.05）.Conclusion：The pregnancy outcome of subclinical hypothyroidism patients in gestation period by thyroid hormones are improved,the pregnancy complication is decreased,so it is worth to promote in clinical.