阿托伐他汀治疗脑梗死患者颈动脉粥样硬化斑块的效果

The Effect of Atorvastatin in Treatment of Carotid Atherosclerotic Plaque in Patients With Cerebral Infarction

目的：探讨阿托伐他汀（立普妥）治疗脑梗死患者颈动脉粥样硬化斑块的效果。方法选择2008年11月～2014年11月我院收治的脑梗死患者150例，对照组给予常规治疗，治疗组在此基础上加用立普妥治疗，治疗周期为4周。结果所有患者都完成治疗，两组治疗后颈动脉内膜中层厚度和斑块面积都低于治疗前（P〈0.05），同时治疗后治疗组的颈动脉内膜中层厚度和斑块面积低于对照组（P〈0.05）。结论立普妥治疗脑梗死患者能有效改善颈动脉粥样硬化斑块状况。

Objective To discuss the ef ect of atorvastatin in treatment of carotid atherosclerotic plaque in patients with cerebral infarction. Methods 150 cases of cerebral infarction patients were select from November 2008 to November 2014 in our hospital. The control group was given conventional therapy while treatment group was added atorvastatin,the treatment period was 4 weeks. Results Al patients completed treatment. After treatment,the carotid intima-media thickness and plaque area were significantly lower than before treatment（P〈0.05）. And carotid intima-media thickness and plaque area of treatment group were obviously lower than that of control group （P〈0.05）. Conclusion The use of atorvastatin for treatment in patients with cerebral infarction can ef ectively improve the state of carotid atherosclerotic plaque.