观察卡前列素氨丁三醇治疗乏力性产后出血的临床疗效

To Observe the Clinical Effect of Carboprost Tromethamine in Treatment of Postpartum Hemorrhage Caused by Uterine Inertia

目的观察卡前列素氨丁三醇用于治疗乏力性产后出血100例临床疗效。方法通过对在我医院接受因为产后宫缩乏力导致出血的100例患者,在运用米索前列醇和缩宫素治疗无效后,再运用卡前列素氨丁三醇进行适量的宫体注射,可重复注射,每次间隔15 min以上,观察并记录患者的治疗效果和出血量。结果 100例患者中有95例患者效果明显,有效率高达95%,剩余5例患者中有3例剖宫产患者在手术中注射卡前列素氨丁三醇500μg,其子宫的收缩能力仍然不好;1例患者进行阴道分娩时注射卡前列素氨丁三醇后,子宫出血仍然没有改观,导致凝血功能的障碍;还有1例患者进行子宫背带式的缝合手术。结论卡前列素氨丁三醇对于治疗乏力性产后出血具有显著的效果,对于患者来说,及时使用效果较好。

Objective To observe the clinical effect of carboprost tromethamine in treatment of postpartum hemorrhage caused by uterine inertia. Methods 100 patients with postpartum hemorrhage caused by uterine inertia in our hospital were selected. When patients used of misoprostol and oxytocin treatment was invalid,then used intrauterine injection amount of carboprost tromethamine,it can repeat injection,but more than 15 min each time interval. To observe and record treatment effect and amount of bleeding with patients. Results In 100 cases,95 cases of patients has obvious effect,the effective rate was as high as 95%. In the remaining 5 patients,3 cases of patients with cesarean section who were injected with carboprost tromethamine 500μg in the operation had no effect. There was 1 patient injected with carboprost tromethamine in vaginal childbirth,the situation of uterine bleeding had no change and leaded to blood coagulation function disorder. There was 1 case of patient with uterine strap suture operation. Conclusion The effect of carboprost tromethamine in treatment of postpartum hemorrhage caused by uterine inertia has remarkable effect and it wil have better effect when it is used in time.