妊娠晚期超敏C反应蛋白对子痫前期患者妊娠结局的影响

Effect of high sensitive C-reactive protein in late pregnancy on pregnancy outcomes in women with preeclampsia

目的探讨妊娠晚期超敏C反应蛋白(hsCRP)对子痫前期患者妊娠结局的影响。方法妊娠晚期入院行免疫比浊法检测孕妇空腹血hsCRP水平,观察患者妊娠结局。结果妊娠晚期hsCRP水平异常增加子痫前期孕妇发生早早产风险,但是不增加早产、新生儿低体重、引产或死胎风险。hsCRP水平与子痫前期严重程度、新生儿胎龄、新生儿体重无统计学相关性(P>0.05)。结论妊娠晚期hsCRP对子痫前期孕妇妊娠不良结局预测价值不大。

Objective To investigate the impact of high sensitive C-reactive protein（hsCRP） of the late pregnancy on the pregnancy outcomes in women with preeclampsia. Methods hsCRP of the late pregnancy was detected by immunoturbidimetry in women with preeclampsia. The association of hsCRP and pregnancy outcomes was analyzed. Results Abnormal hsCRP concentration significantly increased the risk of early preterm birth, but not increased the risk of preterm birth, low newborn birth weight and induced labor or dead fetus, hsCRP concentration was not significantly related to the severity of preeclampsia, gestational age and newborn birth weight. Conclusion hsCRP of the late pregnancy is not a good predictor for adverse pregnancy outcomes in women with preeclampsia.