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异动症的发生与研究进展 被引量:2

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摘要 帕金森病(Parkinson's disease,PD)的临床表现包含了运动症状和非运动症状.除了传统的运动症状外,长期服用左旋多巴导致的异动症,即药源性异动症、左旋多巴诱导异动症(levodopa-induced dyskinesia,LID),也可随着病情的进展而逐步出现.PD患者的异动症可在长期应用多巴制剂后出现,也可由所植入脑起博器的电刺激而产生,称为电刺激诱导异动症(stimulation-induced dyskinesia,SID).出现LID或SID的患者共占全部患者的15%.临床观察到,由于DBS术后患者大都仍无法完全停止左旋多巴的服用,因此,现就PD患者的LID和SID做以全面性的综述,为临床患者出现的异动症提供用药或外科手术建议.
出处 《中华神经外科杂志》 CSCD 北大核心 2015年第5期532-534,共3页 Chinese Journal of Neurosurgery
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参考文献22

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二级参考文献47

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