室间隔基底段增厚的超声与临床特征

The clinical and echocardiography features of basal septal hypertrophy

目的探讨室间隔基底段增厚（BSH）的发病情况、临床与超声影像学特征。方法回顾分析1056例社区中老年人群横断面调查资料，阅读分析超声心动图图像，以室间隔基底段厚度≥1．4cm且室间隔基底段／室间隔中段厚度≥1．3为标准诊断BSH，分析其临床资料和超声心动图特征及相关因素。结果本组人群BSH患病率7．39％（95％CI：5．8％～9．0％）。BSH与心血管现有症状不相关（P〉0．05）。多因素Logistic回归发现男性、肥胖、糖尿病、左室舒张末期内径小、左室舒张功能异常发生BSH的风险更高（Pd0．05），OR值分别为0．49（0．29，0．83），1．99（1．18，3．37），2．24（1．35，3．72），0．39（0．26，0．59），1．96（1．01，3．81）。结论BSH为较常见的超声征象，男性、肥胖、糖尿病、左室舒张末期内径小、左室舒张功能异常均与BSH相关。

Objective To explore the prevalence and clinical and echocardiography features of the basal septal hypertrophy（BSH）. Methods Clinical and echocardiography data of 1 056 elderly population in an urban community of Beijing were analyzed. BSH was defined as the thickness of basal interventricular septum ≥1.4 em and basal septal/mid septal ≥1.3. Data were compared between BSH and non-BSH,and the risk factors of BSH were evaluated. Results The prevalence of BSH in this population was 7.39% （95% CI：5.8%-9.0%）. BSH was not associated with current cardiovascular diseases （ P〉0.05）. Its correlates in logistic analysis included male, diabetes mellitus, small end diastolic left ventrieular dimension and abnormal left ventricular diastolic function （ P〈0.05）, with OR 0.49（0.29,0.83）, 1.99（1.18,3.37）, 2.24 （1.35,3.72）,0.39（0.26,0.59）,and 1.96（1.01,3.81）,respectively. Conclusions BSH is common in elderly community population and not associated with cardiovascular diseases. Its risk factors included male, obesity, diabetes mellitus, small end diastolic left ventrieular dimension and abnormal left ventricular diastolic function.