基于三维超声的计算机辅助制定肝癌消融计划的初步研究

Planning of the hepatocellular carcinoma＇s ablation by three-dimensional ultrasound： a preliminary study

目的探讨基于三维超声的计算机辅助肝癌消融计划制定的可行性及应用价值。方法采集肿瘤最大径21～70mm、三维超声图像清晰的39例患者共40个肿瘤灶的三维超声图像进行分割、三维可视化。采用计算机对肿瘤的三维超声图像进行布针计划并与基于二维超声的人工消融计划相比，比较两种方法在制定消融计划的成功率、损伤率、耗时和布针次数方面的差异。结果基于三维超声的计算机辅助消融计划与基于二维超声的人工消融计划比较，成功率更高（92．31％对53．85％，P=0．000），损伤率更低（7．50％对25．00％，P=0．034），耗时更短（44．0s对263．0s，P=0．000），布针次数更少（3次对4次，P=0．009）。结论基于三维超声计算机辅助的肝癌消融计划制定比传统方法更高效、安全，具有可行性与临床应用价值。

Objective To discusse the feasibility and application value of the computer-assisted liver cancer ablation planning based on the three dimensional ultrasound. Methods Forty three-dimensional ultrasound images of 39 patients with 40 tumors＇ maximum diameter between 21 to 70 mm were collected and then acquired image segmentation and visualzation. The computer-assisted liver cancer ablation planning based on three dimensional ultrasound was comparied with the artificial ablation planning based on two dimensional ultrasound to find out the differences in the success rate, damage rate,time-consuming and the number of insertions between these two methods. Results Compared with the artificial ablation planning based on two dimensional ultrasound, the computer-assisted liver cancer ablation planning had a higher success rate（92.31% vs 53.85%, P = 0.000） ,lower damage rate（7.50% vs 25.00%, P = 0.034） ,shorter time-consuming（44.0 s vs 263.0 s, P = 0.000） and less insersion times（3 vs 4, P = 0.009）. Conclusions The computer-assisted liver cancer ablation planning based on three dimensional ultrasound is more efficient and safety than the traditional way.