46例肺癌合并上腔静脉综合征的临床分析

Clinical analysis of 46 cases of lung cancer complicated with superior vena cava syndrome

目的:回顾分析肺癌合并上腔静脉综合征的放疗效果,探讨上腔静脉综合征的最佳放疗方式。方法:46例肺癌合并上腔静脉综合征患者,常规剂量放疗组20例,大剂量冲击放疗组26例,治疗结束后分析比较疗效。结果:两组照射方法均具有较好的近期疗效,冲击放疗组7天内症状缓解率明显高于常规剂量放疗组,并且不良反应不增加。但两组比较完全缓解率、总缓解率及长期生存率无显著性差异。结论:对于病情较重、病期较晚无法耐受化疗的肺癌合并上腔静脉综合征患者,大剂量冲击放疗能迅速缓解症状,近期疗效较好,不良反应可以耐受,值得进一步推广。

Objective：To explore the best radiotherapy method for lung cancer complicated with superior vena cava syndrome（ SVCS）. Methods：The radiotherapy methods of 46 patients with the disease were retrospectively analyzed by dividing them into two groups：20 patients were given conventional dose radiotherapy and 26 patients were given high dose impact radiotherapy. Results：Both groups of irradiation method has better recent curative effect,the impact of radiotherapy group within 7 days of symptom remission rate was significantly higher than that of conventional dose radiotherapy group,and without increasing side effects. But the complete remission rate,total remission rate and long-term survival rate had no significant difference. Conclusion：In the treatment of lung cancer complicated with supe-rior vena cava syndrome,high-dose radiotherapy can quickly relieve symptoms,and the recent curative effect is bet-ter,side effects can be tolerated.