前列地尔对终末期肝病患者肾保护作用分析

Analysis of renal protective effect of Alprostadil on patients with end- stage liver diseases

目的:讨论分析前列地尔对末期肝病患者肾的保护。方法:80例患者依据药剂量分为4组,观察各组患者的临床情况,对比各组患者的治疗结果。结果:在疗程结束后,各组患者的症状都有不同程度的改善,尿量以及肌酐清除增加,并且使用前列地尔每天80μg,可以达到最好的治疗效果。结论:结果显示,每天使用前列地尔80μg是最佳的治疗效果,它对肝病末期患者的肾脏有一定的保护作用。

Objective： To discuss and analyze renal protecctive effect of Alprostadil on patients with end- stage liver diseases.Methods： 80 patients were divided into 4 groups according to dose. The clinical situation of each group was observed,and the effeccts of these groups were compared. Results： After the end of treatment,the symptoms of the patients in each group had different degrees of improvement,and increased urine output and creatinine clearance occurred. The use of Alprostadil 80 μg / day,you can achieve the best therapeutic effect. Conclusions： The results show that the use of Alprostadil 80 μg / day has the best therapeutic effect,and has a certain renal protective effects for the patients with end- stage liver diseases.