Rh阳性患者接受Rh阴性尸体供肾肾移植2例并文献复习

Rh-positive patients receiving kidney grafts from Rh-negative cadaver donor:a report of two cases and literature review

目的探讨Rh阳性患者接受Rh阴性尸体供肾肾移植的安全性。方法 2013年11月29日,第四军医大学西京医院泌尿外科为两例Rh阳性患者实施Rh阴性尸体供肾肾移植术。回顾性分析两例患者的临床资料并复习相关文献。结果两例患者手术成功,术后均未出现超急性排斥反应或急性排斥反应。随访12个月,移植肾存活良好,患者无明显不适。结论通过术前加强免疫抑制,充分灌注及严密术后监测,Rh阳性患者接受Rh阴性尸体供肾肾移植是安全的。

Objective To discuss the safety of Rh-positive patients receiving kidney grafts from Rh-negative cadaver donor. Methods On November 29 th 2013, two Rh-positive patients received renal transplantation with kidney grafts from Rh-negative cadaver donor at the Department of Urinary Surgery of Xijing Hospital,the Fourth Military Medical University. The clinical data of the two patients were analyzed retrospectively and the relevant literatures were reviewed. Results The two patients underwent renal transplantation successfully and no hyperacute rejection or acute rejection occured after the surgery.The two patients were followed up for 12 months.The kidney grafts survived well and the patients had no obvious discomfort.Conclusions Through enhanced immunosuppression before operation,sufficient perfusion and close postoperative monitoring,it is safe for Rh-positive patients receiving kidney grafts from Rh-negative cadaver donor.